The Metabolic Medicine and Endocrinology Research Theme includes the following sub-groups:
- Endocrine disorders
- Metabolic disorders
- Developmental programming
- Nutrient sensing and homeostasis
- Molecular mechanisms
- Mitochondrial physiology
- Epidemiology
- Placental development and function
- Stem cells and neurological disease
- Therapeutic development
Principal Investigators in this theme:
| Name: Dr Catherine Aiken Topic: metabolism in pregnancy reproductive aging developmental programming Themes: Reproduction, Development and Lifelong Health, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Obstetrics and Gynaecology Email: cema2@cam.ac.uk Website: https://www.obgyn.cam.ac.uk/staff/senior-staff/dr-catherine-aiken/ Applications from potential students are welcome |
| Name: Dr Irving Aye Topic: Metabolic control of epigenetics during early placental development Themes: Reproduction, Development and Lifelong Health, Women's Health, Metabolic Medicine and Endocrinology Department: Obstetrics & Gynaecology Email: Ia319@medschl.cam.ac.uk Website: Ayelaboratory.com Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Dr Kathryn Beardsall Topic: Perinatal metabolism: impact on short term care and long term health Themes: Reproduction, Development and Lifelong Health, Metabolic Medicine and Endocrinology Department: Department of Paediatrics Email: kb274@cam.ac.uk Website: http://paediatrics.medschl.cam.ac.uk/about-us/people/senior-academic-sta... Applications from potential students are welcome |
| Name: Dr Clemence Blouet Topic: Neuroscience of appetite and body weight control Themes: Neuroscience, Psychology and Behaviour, Metabolic Medicine and Endocrinology Department: Clinical Biochemistry Email: csb69@medschl.cam.ac.uk Website: www.blouetlab.org; https://www.mrl.ims.cam.ac.uk/staff/dr-clemence-blouet Applications from potential students are welcome |
| Name: Professor Krishna Chatterjee Topic: Molecular endocrinology; nuclear receptors and human disease Themes: Metabolic Medicine and Endocrinology Department: Department of Medicine (Division of Diabetes and Endocrinology / Institute of Metabolic Science) Email: tdw30@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-krishna-chatterjee Sorry no students can be taken this year |
| Name: Dr Maria Chondronikola Topic: Human nutritional physiology and experimental medicine Themes: Reproduction, Development and Lifelong Health, Epidemiology and Public Health, Metabolic Medicine and Endocrinology, Clinical Science Department: Clinical Biochemistry Email: mc2425@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-maria-chondronikola Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Dr Anthony Coll Topic: Molecular control of appetite and obesity Themes: Neuroscience, Psychology and Behaviour, Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: apc36@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-anthony-coll Applications from potential students are welcome |
| Name: Dr. Miguel Constancia Topic: Epigenetics in health and disease Themes: Reproduction, Development and Lifelong Health, Molecules and Cells, Women's Health, Metabolic Medicine and Endocrinology Department: Obstetrics & Gynaecology; Metabolic Research Laboratories (MRL) Email: jmasmc2@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-miguel-constancia Applications from potential students are welcome |
| Name: Professor Emeritus Timothy Cox Topic: Lysosomal diseases - specifically pathogenesis and therapeutic development for sphingolipidoses Themes: Metabolic Medicine and Endocrinology Department: Medicine Email: tmc12@medschl.cam.ac.uk Website: https://www.postgradschl.lifesci.cam.ac.uk/research-themes-1 Sorry no students can be taken this year |
| Name: Dr Laura Dearden Topic: Impact of nutrition in pregnancy on mother and baby hypothalamus Themes: Reproduction, Development and Lifelong Health, Neuroscience, Psychology and Behaviour, Women's Health, Metabolic Medicine and Endocrinology Department: Institute of Metabolic Science Email: ld454@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-laura-dearden Applications from potential students are welcome |
| Name: Professor Mark Evans Topic: Brain glucose and nutrient sensing, hypoglycaemia Themes: Metabolic Medicine and Endocrinology Department: Wellcome Trust MRC Institute of Metabolic Medicine and Department of Medicine Email: mle24@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-mark-evans Applications from potential students are welcome |
| Name: Professor Sadaf Farooqi Topic: Molecular mechanisms in human obesity Themes: Neuroscience, Psychology and Behaviour, Molecules and Cells, Metabolic Medicine and Endocrinology, Clinical Science Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: isf20@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-sadaf-farooqi Applications from potential students are welcome |
| Name: Dr Daniel Fazakerley Topic: Cell Biology of Insulin Action and Resistance Themes: Molecules and Cells, Metabolic Medicine and Endocrinology Department: Clinical Biochemistry Email: djf72@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-daniel-fazakerley Applications from potential students are welcome |
| Name: Dr Alison Forhead Topic: Endocrine control of fetal development and maturation Themes: Reproduction, Development and Lifelong Health, Molecules and Cells, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Physiology Development and Neuroscience Email: ajf1005@cam.ac.uk Website: http://www.pdn.cam.ac.uk/staff/forhead/ Sorry no students can be taken this year |
| Name: Dr Nita Forouhi Topic: Nutritional Epidemiology in relation to diabetes and obesity Themes: Epidemiology and Public Health, Metabolic Medicine and Endocrinology, Clinical Science Department: MRC Epidemiology Unit Email: nita.forouhi@mrc-epid.cam.ac.uk Website: http://www.mrc-epid.cam.ac.uk/research/research-areas/nutrition Applications from potential students are welcome |
| Name: Professor Abigail Fowden Topic: Fetal and placental physiology Themes: Reproduction, Development and Lifelong Health, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Physiology Development and Neuroscience Email: alf1000@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/abigail-fowden Sorry no students can be taken this year |
| Name: Professor Fiona Gribble Topic: Signalling in the gut-brain-pancreatic axis Themes: Molecules and Cells, Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: fmg23@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-fiona-gribble Applications from potential students are welcome |
| Name: Dr Mark Gurnell Topic: Acquired and genetic disorders of hypothalamic-pituitary-thyroid function; functional imaging in endocrine neoplasia; acromegaly Themes: Molecules and Cells, Metabolic Medicine and Endocrinology Department: Department of Medicine (Division of Diabetes and Endocrinology / Institute of Metabolic Science) Email: mg299@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-mark-gurnell Applications from potential students are welcome |
| Name: Professor Judy Hirst Topic: The structure and mechanism, function and medically-relevant dysfunction, of mitochondrial complex I (NADH:ubiquinone oxidoreductase) Themes: Molecules and Cells, Metabolic Medicine and Endocrinology Department: MRC Mitochondrial Biology Unit Email: judy.hirst@mrc-mbu.cam.ac.uk Website: https://www.mrc-mbu.cam.ac.uk/research-groups/hirst-group Applications from potential students are welcome |
| Name: Dr Matthew Hoare Topic: Chronic liver disease and cancer development Themes: Cancer, Metabolic Medicine and Endocrinology Department: Early Cancer Institute Email: mwh20@cam.ac.uk Website: https://www.earlycancer.cam.ac.uk/dr-matt-hoare Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Dr Nicola Holdstock Topic: Neonatal medicine and physiology Themes: Reproduction, Development and Lifelong Health, Metabolic Medicine and Endocrinology Department: Department of Veterinary Medicine Email: nbh10@cam.ac.uk Website: http://www.vet.cam.ac.uk/directory/nbh10@cam.ac.uk/ Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Professor Roman Hovorka Topic: Relationship between insulin sensitivity and insulin secretion. Longitudinal analysis of metabolic disturbances in Type 2 diabetes. Artificial pancreas Themes: Reproduction, Development and Lifelong Health, Metabolic Medicine and Endocrinology Department: Department of Paediatrics (Institute of Metabolic Science) Email: rh347@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-roman-hovorka Applications from potential students are welcome |
| Name: Professor Arthur Kaser Topic: Metabo-genetics of autoinflammation/autoimmunity (focus on Crohn's and Still's disease). Core metabolism of the cell. Themes: Cancer, Functional and Evolutionary Genomics, Infection and Immunity, Molecules and Cells, Metabolic Medicine and Endocrinology Department: Department of Medicine & Cambridge Institute of Therapeutic Immunology and Infectious Disease Email: ak729@cam.ac.uk Website: https://www.citiid.cam.ac.uk/arthur-kaser/ Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Dr Albert Koulman Topic: Development of mass spectrometry for metabolomics and lipidomics Themes: Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: ak675@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-albert-koulman Applications from potential students are welcome |
| Name: Dr Wei Li Topic: Molecular basis of TGFß/BMP signalling in cardiovascular diseases Themes: Cardiovascular Science and Medicine, Molecules and Cells, Metabolic Medicine and Endocrinology Department: Medicine Email: wl225@cam.ac.uk Website: https://www.cardiovascular.cam.ac.uk/directory/wli Applications from potential students are welcome |
| Name: Professor Eoin McKinney Topic: Autoimmunity, Inflammatory disease, immunology, genomics, Machine Learning Themes: Functional and Evolutionary Genomics, Infection and Immunity, Molecules and Cells, Metabolic Medicine and Endocrinology Department: Medicine Email: efm30@cam.ac.uk Website: https://www.immunology.cam.ac.uk/departments/cambridge-institute-for-the... Applications from potential students are welcome |
| Name: Dr Florian Merkle Topic: Understanding the cellular and molecular basis of neurological disease using human stem cell-derived and animal model systems Themes: Functional and Evolutionary Genomics, Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: fm436@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/dr-florian-merkle Applications from potential students are welcome |
| Name: Dr Michael Murphy Topic: Targeting molecules to mitochondria mitochondrial radical production thiol redox state and redox signalling Themes: Cardiovascular Science and Medicine, Molecules and Cells, Metabolic Medicine and Endocrinology Department: MRC Mitochondrial Biology Unit Email: michael.murphy@mrc-mbu.cam.ac.uk Website: http://www.mrc-mbu.cam.ac.uk/people/mike-murphy Applications from potential students are welcome |
| Name: Professor Andrew Murray Topic: Mitochondrial physiology in health and disease Themes: Cardiovascular Science and Medicine, Reproduction, Development and Lifelong Health, Molecules and Cells, Metabolic Medicine and Endocrinology Department: Department of Physiology Development and Neuroscience Email: ajm267@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/andrew-murray Applications from potential students are welcome |
| Name: Professor Ken Ong Topic: Childhood obesity, growth and development, and relationships to adult metabolic disease Themes: Reproduction, Development and Lifelong Health, Epidemiology and Public Health, Metabolic Medicine and Endocrinology, Clinical Science Department: MRC Epidemiology Unit / Department of Paediatrics Email: ken.ong@mrc-epid.cam.ac.uk Website: https://www.mrc-epid.cam.ac.uk/people/ken-ong/ Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
| Name: Professor Stephen O'Rahilly Topic: The endocrine control of metabolism in health and disease Themes: Cardiovascular Science and Medicine, Reproduction, Development and Lifelong Health, Functional and Evolutionary Genomics, Neuroscience, Psychology and Behaviour, Molecules and Cells, Metabolic Medicine and Endocrinology, Clinical Science Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: so104@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-sir-stephen-orahilly Applications from potential students are welcome |
| Name: Professor Susan Ozanne Topic: Developmental Origins of Health and Disease Themes: Cardiovascular Science and Medicine, Reproduction, Development and Lifelong Health, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: seo10@cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-susan-ozanne Applications from potential students are welcome |
| Name: Dr Luca Peruzzotti-Jametti Topic: Molecular mechanisms Stem cells and neurological disease Mitochondrial physiology Themes: Metabolic Medicine and Endocrinology Department: Department: Department of Clinical Neurosciences (Neurology unit) Email: lp429@cam.ac.uk Website: https://neuroscience.cam.ac.uk/member/lperuzzotti/ Applications from potential students are welcome |
| Name: Dr Eleanor Raffan Topic: Metabolic disease including obesity - molecular, genetic and physiological aspects; animal genetics Themes: Department: Physiology, Development and Neuroscience & Institute of Metabolic Science Email: er311@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/eleanor-raffan Applications from potential students are welcome |
| Name: Dr Eleanor Raffan Topic: Metabolic disease and obesity - molecular, genetic and physiological insights from spontaneous veterinary models of disease. Also interspecies communication! Themes: Functional and Evolutionary Genomics, Neuroscience, Psychology and Behaviour, Metabolic Medicine and Endocrinology, Clinical Science Department: PDN Email: er311@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/eleanor-raffan Applications from potential students are welcome |
| Name: Professor Frank Reimann Topic: Stimulus-secretion coupling in gut neuroendocrine cells Themes: Neuroscience, Psychology and Behaviour, Molecules and Cells, Metabolic Medicine and Endocrinology Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: fr222@cam.ac.uk Website: ttps://www.mrl.ims.cam.ac.uk/staff/professor-frank-reimann Applications from potential students are welcome |
| Name: Professor David Savage Topic: Mechanisms of insulin resistance Themes: Molecules and Cells, Metabolic Medicine and Endocrinology, Clinical Science Department: Department of Clinical Biochemistry (Institute of Metabolic Science) Email: dbs23@medschl.cam.ac.uk Website: https://www.mrl.ims.cam.ac.uk/staff/professor-david-savage Applications from potential students are welcome |
| Name: Professor Amanda Sferruzzi-Perri Topic: Placental development and function and its relevance for pregnancy success and life-long health Themes: Cardiovascular Science and Medicine, Reproduction, Development and Lifelong Health, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Physiology Development and Neuroscience Email: ans48@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/amanda-sferruzzi-perri Applications from potential students are welcome |
| Name: Dr Alecia-Jane Twigger Topic: Lactation; biosynthesis; mammary gland biology; womens health Themes: Reproduction, Development and Lifelong Health, Epidemiology and Public Health, Molecules and Cells, Women's Health, Metabolic Medicine and Endocrinology Department: Biochemistry and Pharmacology Email: ajt215@cam.ac.uk Website: https://www.cambridgelactationlab.com/ Applications from potential students are welcome |
| Name: Dr Jelle van den Ameele Topic: Neural stem cell metabolism, mitochondrial genetics, gene expression, chromatin, mitochondrial disease Themes: Reproduction, Development and Lifelong Health, Functional and Evolutionary Genomics, Neuroscience, Psychology and Behaviour, Molecules and Cells, Metabolic Medicine and Endocrinology, Clinical Science Department: Department of Clinical Neurosciences Email: jv361@cam.ac.uk Website: https://www.mrc-mbu.cam.ac.uk/research-groups/van-den-ameele-group Applications from potential students are welcome |
| Name: Dr Erica Watson Topic: Mechanisms of folate metabolism during development Themes: Reproduction, Development and Lifelong Health, Molecules and Cells, Women's Health, Metabolic Medicine and Endocrinology Department: Department of Physiology Development and Neuroscience Email: edw23@cam.ac.uk Website: https://www.pdn.cam.ac.uk/directory/watson-erica Sorry no vacation students can be taken this year but enquiries from potential PhD students are welcome |
